MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms

MacroH2A histone variants suppress tumor progression and act as epigenetic barriers to induced pluripotency. How they impart their influence on chromatin plasticity is not well understood. Here, we analyze how the different domains of macroH2A proteins contribute to chromatin structure and dynamics.

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Bibliographische Detailangaben
Hauptverfasser: Kozłowski, Marek (VerfasserIn) , Scheffzek, Klaus (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 3 September 2018
In: EMBO reports
Year: 2018, Jahrgang: 19, Heft: 10
ISSN:1469-3178
DOI:10.15252/embr.201744445
Online-Zugang:Resolving-System, Volltext: https://doi.org/10.15252/embr.201744445
Verlag: https://www.embopress.org/doi/full/10.15252/embr.201744445
Volltext
Verfasserangaben:Marek Kozlowski, David Corujo, Michael Hothorn, Iva Guberovic, Imke K Mandemaker, Charlotte Blessing, Judith Sporn, Arturo Gutierrez-Triana, Rebecca Smith, Thomas Portmann, Mathias Treier, Klaus Scheffzek, Sebastien Huet, Gyula Timinszky, Marcus Buschbeck & Andreas G Ladurner

MARC

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