MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms
MacroH2A histone variants suppress tumor progression and act as epigenetic barriers to induced pluripotency. How they impart their influence on chromatin plasticity is not well understood. Here, we analyze how the different domains of macroH2A proteins contribute to chromatin structure and dynamics.
Gespeichert in:
| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
3 September 2018
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| In: |
EMBO reports
Year: 2018, Jahrgang: 19, Heft: 10 |
| ISSN: | 1469-3178 |
| DOI: | 10.15252/embr.201744445 |
| Online-Zugang: | Resolving-System, Volltext: https://doi.org/10.15252/embr.201744445 Verlag: https://www.embopress.org/doi/full/10.15252/embr.201744445 
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| Verfasserangaben: | Marek Kozlowski, David Corujo, Michael Hothorn, Iva Guberovic, Imke K Mandemaker, Charlotte Blessing, Judith Sporn, Arturo Gutierrez-Triana, Rebecca Smith, Thomas Portmann, Mathias Treier, Klaus Scheffzek, Sebastien Huet, Gyula Timinszky, Marcus Buschbeck & Andreas G Ladurner |
| Zusammenfassung: | MacroH2A histone variants suppress tumor progression and act as epigenetic barriers to induced pluripotency. How they impart their influence on chromatin plasticity is not well understood. Here, we analyze how the different domains of macroH2A proteins contribute to chromatin structure and dynamics. |
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| Beschreibung: | Gesehen am 30.01.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1469-3178 |
| DOI: | 10.15252/embr.201744445 |