EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association

Abstract. The transcriptional regulator EVI1 has an essential role in early hematopoiesis and development. However, aberrantly high expression of EVI1 has pote

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Autori principali: Paredes, Roberto (Autore) , Löffler, Harald (Autore)
Natura: Article (Journal)
Lingua:inglese
Pubblicazione: 25 June 2018
In: Nucleic acids research
Year: 2018, Volume: 46, Fascicolo: 15, Pages: 7662-7674
ISSN:1362-4962
DOI:10.1093/nar/gky536
Accesso online:Verlag, Volltext: https://doi.org/10.1093/nar/gky536
Verlag, Volltext: https://academic.oup.com/nar/article/46/15/7662/5043459
Testo
Note sull'autore:Roberto Paredes, Marion Schneider, Adam Stevens, Daniel J. White, Andrew J. K. Williamson, Joanne Muter, Stella Pearson, James R. Kelly, Kathleen Connors, Daniel H. Wiseman, John A. Chadwick, Harald Löffler, Hsiang Ying Teng, Simon Lovell, Richard Unwin, Henri J. van de Vrugt, Helen Smith, Olga Kustikova, Axel Schambach, Tim C. P. Somervaille, Andrew Pierce, Anthony D. Whetton, Stefan Meyer
Descrizione
Riassunto:Abstract. The transcriptional regulator EVI1 has an essential role in early hematopoiesis and development. However, aberrantly high expression of EVI1 has pote
Descrizione del documento:Gesehen am 21.02.2020
Descrizione fisica:Online Resource
ISSN:1362-4962
DOI:10.1093/nar/gky536