NAD-modifizierte RNA: Redox-biochemie trifft RNA-Prozessierung

RNA is an important regulator in biology. Its simple architecture is augmented by diverse chemical modifications. Recently we discovered the ubiquitous redox coenzyme nicotinamide adenine dinucleotide (NAD) to be attached to a specific set of regulatory RNAs in bacteria in a cap-like manner, and to...

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Bibliographic Details
Main Authors: Höfer, Katharina (Author) , Jäschke, Andres (Author)
Format: Article (Journal)
Language:English
Published: 13 November 2018
In: Biospektrum
Year: 2018, Volume: 24, Issue: 7, Pages: 680-683
ISSN:1868-6249
DOI:10.1007/s12268-018-0980-z
Online Access:Verlag, Volltext: https://doi.org/10.1007/s12268-018-0980-z
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Author Notes:Katharina Höfer, Andres Jäschke
Description
Summary:RNA is an important regulator in biology. Its simple architecture is augmented by diverse chemical modifications. Recently we discovered the ubiquitous redox coenzyme nicotinamide adenine dinucleotide (NAD) to be attached to a specific set of regulatory RNAs in bacteria in a cap-like manner, and to modulate the cellular functions of these RNAs. This article highlights the biosynthesis, removal, and biological function of this novel RNA modification.
Item Description:Gesehen am 04.03.2020
Physical Description:Online Resource
ISSN:1868-6249
DOI:10.1007/s12268-018-0980-z