Mepivacaine reduces calcium transients in isolated murine ventricular cardiomyocytes

The potential mechanism of mepivacaine’s myocardial depressant effect observed in papillary muscle has not yet been investigated at cellular level. Therefore, we evaluated mepivacaine’s effects on Ca2+ transient in isolated adult mouse cardiomyocytes.

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Bibliographic Details
Main Authors: Mosqueira, Matias (Author) , Aykut, Güçlü (Author) , Fink, Rainer (Author)
Format: Article (Journal)
Language:English
Published: 08 January 2020
In: BMC anesthesiology
Year: 2020, Volume: 20, Issue: 1
ISSN:1471-2253
DOI:10.1186/s12871-019-0926-0
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12871-019-0926-0
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Author Notes:Matias Mosqueira, Güçlü Aykut and Rainer H.A. Fink
Description
Summary:The potential mechanism of mepivacaine’s myocardial depressant effect observed in papillary muscle has not yet been investigated at cellular level. Therefore, we evaluated mepivacaine’s effects on Ca2+ transient in isolated adult mouse cardiomyocytes.
Item Description:Gesehen am 05.03.2020
Physical Description:Online Resource
ISSN:1471-2253
DOI:10.1186/s12871-019-0926-0