Regorafenib for patients with metastatic colorectal cancer who progressed after standard therapy: results of the large, single‐arm, open‐label phase IIIb CONSIGN study

This article reports the results of the CONSIGN study, which was designed to characterize the safety of regorafenib in a large patient population, estimate progression‐free survival, and provide patients with treatment‐refractory metastatic colorectal cancer access to regorafenib before market autho...

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Bibliographic Details

Main Authors:	Van Cutsem, Eric (Author) , Martinelli, Erika (Author) , Cascinu, Stefano (Author) , Sobrero, Alberto (Author) , Banzi, Maria (Author) , Seitz, Jean‐François (Author) , Barone, Carlo (Author) , Ychou, Marc (Author) , Peeters, Marc (Author) , Brenner, Baruch (Author) , Hofheinz, Ralf-Dieter (Author) , Maiello, Evaristo (Author) , André, Thierry (Author) , Spallanzani, Andrea (Author) , Garcia‐Carbonero, Rocio (Author) , Arriaga, Yull E. (Author) , Verma, Udit (Author) , Grothey, Axel (Author) , Kappeler, Christian (Author) , Miriyala, Ashok (Author) , Kalmus, Joachim (Author) , Falcone, Alfredo (Author) , Zaniboni, Alberto (Author)
Format:	Article (Journal)
Language:	English
Published:	2019
In:	The oncologist Year: 2018, Volume: 24, Issue: 2, Pages: 185-192
ISSN:	1549-490X
DOI:	10.1634/theoncologist.2018-0072
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1634/theoncologist.2018-0072 Verlag, lizenzpflichtig, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369948/
Author Notes:	Eric Van Cutsem, Erika Martinelli, Stefano Cascinu, Alberto Sobrero, Maria Banzi, Jean‐François Seitz, Carlo Barone, Marc Ychou, Marc Peeters, Baruch Brenner, Ralf Dieter Hofheinz, Evaristo Maiello, Thierry André, Andrea Spallanzani, Rocio Garcia‐Carbonero, Yull E. Arriaga, Udit Verma, Axel Grothey, Christian Kappeler, Ashok Miriyala, Joachim Kalmus, Alfredo Falcone, Alberto Zaniboni