Targeted therapy of HER2-negative breast cancer

Personalized and targeted treatments are the most discussed topics in oncology. However, how much personalized medicine is standard of care nowadays and how much is part of our hope for a better future? So far, only a few targeted therapies are available in daily practice for the treatment of human...

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Hauptverfasser: Schütz, Florian (Verfasst von) , Domschke, Christoph (Verfasst von) , Schneeweiss, Andreas (Verfasst von)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: February 10, 2016
In: Oncology research and treatment
Year: 2016, Jahrgang: 39, Heft: 3, Pages: 118-121
ISSN:2296-5262
DOI:10.1159/000444204
Online-Zugang:Verlag, Volltext: https://doi.org/10.1159/000444204
Verlag, Volltext: https://www.karger.com/Article/FullText/444204
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Verfasserangaben:Florian Schütz, Christoph Domschke, Andreas Schneeweiss
Beschreibung
Zusammenfassung:Personalized and targeted treatments are the most discussed topics in oncology. However, how much personalized medicine is standard of care nowadays and how much is part of our hope for a better future? So far, only a few targeted therapies are available in daily practice for the treatment of human epidermal growth factor receptor 2 (HER2)-negative breast cancer. And even for these few targeted agents - besides those targeting the estrogen receptor (ER) for endocrine treatment - thus far, predictive factors are missing. There are many new drugs and strategies under evaluation but, unfortunately, they are being developed without any cross-comparison. What drug will we choose for which patient in the future? Without answering this question oncologists will not be able to individualize treatment. Predictive factors for every new splendid drug are eagerly needed before it comes to an approval.
Beschreibung:Gesehen am 09.03.2020
Beschreibung:Online Resource
ISSN:2296-5262
DOI:10.1159/000444204