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Comparison of three prognostic models for predicting cancer-specific survival among patients with gastrointestinal stromal tumors

Aim: To evaluate the predictive value for cancer-specific survival of the models of the American Joint Committee on Cancer (AJCC) stage, NIH and Armed Forces Institute of Pathology (AFIP) among patients with gastrointestinal stromal tumors (GISTs). Methods: Surveillance, Epidemiology and End Results...

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Main Authors: Oweira, Hani (Author) , Schmidt, Jan (Author) , Mehrabi, Arianeb (Author) , Kulaksiz, Hasan (Author) , Schneider, Paul (Author) , Schöb, Othmar (Author) , Giryes, Anwar (Author) , Abdel-Rahman, Omar (Author)
Format: Article (Journal)
Language:English
Published: 10 Jan 2018
In: Future oncology
Year: 2018, Volume: 14, Issue: 4, Pages: 379-389
ISSN:1744-8301
DOI:10.2217/fon-2017-0450
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.2217/fon-2017-0450
Verlag, lizenzpflichtig, Volltext: https://www.futuremedicine.com/doi/10.2217/fon-2017-0450
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Author Notes:Hani Oweira, Jan Schmidt, Arianeb Mehrabi, Hasan Kulaksiz, Paul Schneider, Othmar Schöb, Anwar Giryes, Omar Abdel-Rahman
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Summary:Aim: To evaluate the predictive value for cancer-specific survival of the models of the American Joint Committee on Cancer (AJCC) stage, NIH and Armed Forces Institute of Pathology (AFIP) among patients with gastrointestinal stromal tumors (GISTs). Methods: Surveillance, Epidemiology and End Results database (2010-2014) was accessed. Overall survival analysis and adjusted cancer-specific Cox regression hazard was calculated. Results: For gastric GISTs, concordance-index according to AJCC was 0.834; according to NIH was 0.833; according to AFIP was 0.836. Concordance-index for nongastric GISTs according to AJCC was 0.800, according to NIH was 0.801 and according to AFIP was 0.799. Conclusion: The performance of the three models is comparable with regards to cancer-specific survival prediction.
Item Description:Gesehen am 11.03.2020
Physical Description:Online Resource
ISSN:1744-8301
DOI:10.2217/fon-2017-0450

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