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Randomized trial of pylorus-preserving vs. pylorus-resecting pancreatoduodenectomy: long-term morbidity and quality of life

The randomized controlled PROPP trial (DKRS00004191) showed that pylorus-resecting pancreatoduodenectomy (PR) is not superior to the pylorus-preserving procedure (PP) in terms of perioperative outcome, specifically in reduction of delayed gastric emptying. Non-superiority of PR was also confirmed in...

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Main Authors: Klaiber, Ulla (Author) , Probst, Pascal (Author) , Hüttner, Felix (Author) , Bruckner, Thomas (Author) , Strobel, Oliver (Author) , Diener, Markus K. (Author) , Mihaljevic, André Leopold (Author) , Büchler, Markus W. (Author) , Hackert, Thilo (Author)
Format: Article (Journal)
Language:English
Published: 2020
In: Journal of gastrointestinal surgery
Year: 2020, Volume: 24, Issue: 2, Pages: 341-352
ISSN:1873-4626
DOI:10.1007/s11605-018-04102-y
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s11605-018-04102-y
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Author Notes:Ulla Klaiber, Pascal Probst, Felix J. Hüttner, Thomas Bruckner, Oliver Strobel, Markus K. Diener, André L. Mihaljevic, Markus W. Büchler, Thilo Hackert
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Summary:The randomized controlled PROPP trial (DKRS00004191) showed that pylorus-resecting pancreatoduodenectomy (PR) is not superior to the pylorus-preserving procedure (PP) in terms of perioperative outcome, specifically in reduction of delayed gastric emptying. Non-superiority of PR was also confirmed in a recent meta-analysis of randomized controlled trials. However, long-term data on morbidity and quality of life after PP compared to PR are sparse. The aim of this study was to investigate long-term outcomes of patients included in the PROPP trial.
Item Description:Published online: 22 January 2019
Gesehen am 26.03.2020
Physical Description:Online Resource
ISSN:1873-4626
DOI:10.1007/s11605-018-04102-y

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