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Antibody responses to cancer antigens identify patients with a poor prognosis among HPV-positive and HPV-negative head and neck squamous cell carcinoma patients

The identification of high-risk patients within human papillomavirus (HPV)-positive and -negative head and neck squamous cell carcinoma (HNSCC) is needed for improved treatment and surveillance strategies. In this study, we set out to discover antibody responses (AR) with prognostic impact in HNSCC...

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Main Authors: Laban, Simon Andreas (Author) , Gangkofner-Strauss, Dominik Stefan (Author) , Holzinger, Dana (Author) , Schroeder, Lea (Author) , Eichmüller, Stefan B. (Author) , Zörnig, Inka (Author) , Jäger, Dirk (Author) , Wichmann, Gunnar (Author) , Dietz, Andreas (Author) , Broglie, Martina A. (Author) , Herold-Mende, Christel (Author) , Dyckhoff, Gerhard (Author) , Boscolo-Rizzo, Paolo (Author) , Ezić, Jasmin (Author) , Marienfeld, Ralf (Author) , Möller, Peter (Author) , Kraus, Johann M. (Author) , Völkel, Gunnar (Author) , Kestler, Hans A. (Author) , Brunner, Cornelia (Author) , Schuler, Patrick (Author) , Wigand, Marlene C. (Author) , Theodoraki, Marie-Nicole (Author) , Doescher, Johannes (Author) , Hoffmann, Thomas K. (Author) , Pawlita, Michael (Author) , Waterboer, Tim (Author) , Butt, Julia (Author)
Format: Article (Journal)
Language:English
Published: August 23, 2019
In: Clinical cancer research
Year: 2019, Volume: 25, Issue: 24, Pages: 7405-7412
ISSN:1557-3265
DOI:10.1158/1078-0432.CCR-19-1490
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1158/1078-0432.CCR-19-1490
Verlag, lizenzpflichtig, Volltext: https://clincancerres.aacrjournals.org/content/25/24/7405
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Author Notes:Simon Laban, Dominik S. Gangkofner, Dana Holzinger, Lea Schroeder, Stefan B. Eichmüller, Inka Zörnig, Dirk Jäger, Gunnar Wichmann, Andreas Dietz, Martina A. Broglie, Christel C. Herold-Mende, Gerhard Dyckhoff, Paolo Boscolo-Rizzo, Jasmin Ezić, Ralf Marienfeld, Peter Möller, Johann M. Kraus, Gunnar Völkel, Hans A. Kestler, Cornelia Brunner, Patrick J. Schuler, Marlene C. Wigand, Marie-Nicole Theodoraki, Johannes Doescher, Thomas K. Hoffmann, Michael Pawlita, Tim Waterboer, and Julia Butt
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Summary:The identification of high-risk patients within human papillomavirus (HPV)-positive and -negative head and neck squamous cell carcinoma (HNSCC) is needed for improved treatment and surveillance strategies. In this study, we set out to discover antibody responses (AR) with prognostic impact in HNSCC stratified by HPV status.
Item Description:Gesehen am 31.03.2020
Physical Description:Online Resource
ISSN:1557-3265
DOI:10.1158/1078-0432.CCR-19-1490

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