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FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas

In search of novel genes associated with glioma pathogenesis, we have previously shown frequent deletions of the KIAA1797/FOCAD gene in malignant gliomas, and a tumor suppressor function of the encoded focadhesin impacting proliferation and migration of glioma cells in vitro and in vivo. Here, we ex...

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Main Authors: Brand, Frank (Author) , Förster, Alisa (Author) , Christians, Anne (Author) , Bucher, Martin (Author) , Thomé, Carina M. (Author) , Raab, Marc-Steffen (Author) , Westphal, Manfred (Author) , Pietsch, Torsten (Author) , Deimling, Andreas von (Author) , Reifenberger, Guido (Author) , Claus, Peter (Author) , Hentschel, Bettina (Author) , Weller, Michael (Author) , Weber, Ruthild G. (Author)
Format: Article (Journal)
Language:English
Published: 2020
In: Acta neuropathologica
Year: 2019, Volume: 139, Issue: 1, Pages: 175-192
ISSN:1432-0533
DOI:10.1007/s00401-019-02067-z
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00401-019-02067-z
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Author Notes:Frank Brand, Alisa Förster, Anne Christians, Martin Bucher, Carina M. Thomé, Marc S. Raab, Manfred Westphal, Torsten Pietsch, Andreas von Deimling, Guido Reifenberger, Peter Claus, Bettina Hentschel, Michael Weller, Ruthild G. Weber

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