On the limitations of the area under the ROC curve for NTCP modelling

The area under the ROC curve (AUC) is commonly used as a measure for the discriminative performance of NTCP models. Here, we demonstrate that for typical patient cohorts, the AUC is an unsuitable measure for that purpose since it is typically limited to values below 0.8 and it exhibits large statist...

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Bibliographic Details
Main Authors: Bahn, Emanuel (Author) , Alber, Markus (Author)
Format: Article (Journal)
Language:English
Published: 2020
In: Radiotherapy and oncology
Year: 2019, Volume: 144, Pages: 148-151
ISSN:1879-0887
DOI:10.1016/j.radonc.2019.11.018
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.radonc.2019.11.018
Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0167814019334887
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Author Notes:Emanuel Bahn, Markus Alber
Description
Summary:The area under the ROC curve (AUC) is commonly used as a measure for the discriminative performance of NTCP models. Here, we demonstrate that for typical patient cohorts, the AUC is an unsuitable measure for that purpose since it is typically limited to values below 0.8 and it exhibits large statistical variation.
Item Description:Available online 5 December 2019
Gesehen am 02.04.2020
Physical Description:Online Resource
ISSN:1879-0887
DOI:10.1016/j.radonc.2019.11.018