Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach

Reactivation of the telomerase reverse transcriptase gene TERT is a central feature for unlimited proliferation of the majority of cancers. However, the underlying regulatory processes are only partly understood.

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Bibliographic Details
Main Authors: Poos, Alexandra (Author) , Kordaß, Theresa (Author) , Kolte, Amol (Author) , Ast, Volker (Author) , Oswald, Marcus (Author) , Rippe, Karsten (Author) , König, Rainer (Author)
Format: Article (Journal)
Language:English
Published: 30 December 2019
In: BMC bioinformatics
Year: 2019, Volume: 20
ISSN:1471-2105
DOI:10.1186/s12859-019-3323-2
Online Access:Resolving-System, kostenfrei, Volltext: https://doi.org/10.1186/s12859-019-3323-2
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Author Notes:Alexandra M. Poos, Theresa Kordaß, Amol Kolte, Volker Ast, Marcus Oswald, Karsten Rippe and Rainer König
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Summary:Reactivation of the telomerase reverse transcriptase gene TERT is a central feature for unlimited proliferation of the majority of cancers. However, the underlying regulatory processes are only partly understood.
Item Description:Gesehen am 03.04.2020
Physical Description:Online Resource
ISSN:1471-2105
DOI:10.1186/s12859-019-3323-2