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Transplantation of marginal organs: immunological aspects and therapeutic perspectives in kidney transplantation

Recent data from the World Population Prospects projects that by 2050, nearly all regions in the world will have a quarter or more of the population aged 60 and above. Chronic kidney disease (CKD) has a high global prevalence (around 13%) worldwide and the prevalence of CKD and end-stage kidney dise...

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Bibliographic Details
Main Authors: Noble, Johan (Author) , Jouve, Thomas (Author) , Malvezzi, Paolo (Author) , Süsal, Caner (Author) , Rostaing, Lionel (Author)
Format: Article (Journal)
Language:English
Published: 31 January 2020
In: Frontiers in immunology
Year: 2020, Volume: 10
ISSN:1664-3224
DOI:10.3389/fimmu.2019.03142
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.3389/fimmu.2019.03142
Verlag, lizenzpflichtig, Volltext: https://www.frontiersin.org/articles/10.3389/fimmu.2019.03142/full
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Author Notes:Johan Noble, Thomas Jouve, Paolo Malvezzi, Caner Süsal and Lionel Rostaing
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Summary:Recent data from the World Population Prospects projects that by 2050, nearly all regions in the world will have a quarter or more of the population aged 60 and above. Chronic kidney disease (CKD) has a high global prevalence (around 13%) worldwide and the prevalence of CKD and end-stage kidney disease (ESKD) increase with age. Kidney transplantation remains the best therapeutic option for ESKD, offering a survival benefit in comparison with dialysis maintenance for most patients. This review focuses on immunological aspects of kidney transplantation in older patients and marginal donors i.e. 60 years or older deceased kidney donors or 50 to 59 years old deceased kidney donors with comorbidities.
Item Description:Gesehen am 08.04.2020
Physical Description:Online Resource
ISSN:1664-3224
DOI:10.3389/fimmu.2019.03142

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