Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial

Background - Young children with medulloblastoma have a poor overall survival compared with older children, due to use of radiation-sparing therapy in young children. Radiotherapy is omitted or reduced in these young patients to spare them from debilitating long-term side-effects. We aimed to estima...

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Bibliographic Details

Main Authors:	Robinson, Giles W. (Author) , Korbel, Jan Oliver (Author) , Jones, David T. W. (Author) , Lichter, Peter (Author) , Kool, Marcel (Author) , Pfister, Stefan (Author)
Format:	Article (Journal)
Language:	English
Published:	May 16, 2018
In:	The lancet. Oncology Year: 2018, Volume: 19, Issue: 6, Pages: 768-784
ISSN:	1474-5488
DOI:	10.1016/S1470-2045(18)30204-3
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/S1470-2045(18)30204-3 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S1470204518302043
Author Notes:	Giles W Robinson, Vasilisa A Rudneva, Ivo Buchhalter, Catherine A Billups, Sebastian M Waszak, Kyle S Smith, Daniel C Bowers, Anne Bendel, Paul G Fisher, Sonia Partap, John R Crawford, Tim Hassall, Daniel J Indelicato, Frederick Boop, Paul Klimo, Noah D Sabin, Zoltan Patay, Thomas E Merchant, Clinton F Stewart, Brent A Orr, Jan O Korbel, David T W Jones, Tanvi Sharma, Peter Lichter, Marcel Kool, Andrey Korshunov, Stefan M Pfister, Richard J Gilbertson, Robert P Sanders, Arzu Onar-Thomas, David W Ellison, Amar Gajjar, Paul A Northcott