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Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Joana Carlevaro-Fita, Andrés Lanzós et al. present the Cancer LncRNA Census (CLC), a manually curated dataset of 122 long noncoding RNAs (lncRNAs) with experimentally-validated functions in cancer based on data from the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. CLC lncRNAs...

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Main Authors: Carlevaro-Fita, Joana (Author) , Lanzós, Andrés (Author) , Feuerbach, Lars (Author) , Hong, Chen (Author) , Mas-Ponte, David (Author) , Pedersen, Jakob Skou (Author) , Johnson, Rory (Author)
Other Authors: Herrmann, Carl (Other)
Format: Article (Journal)
Language:English
Published: 05 February 2020
In: Communications biology
Year: 2020, Volume: 3
ISSN:2399-3642
DOI:10.1038/s42003-019-0741-7
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s42003-019-0741-7
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s42003-019-0741-7
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Author Notes:Joana Carlevaro-Fita, Andrés Lanzós, Lars Feuerbach, Chen Hong, David Mas-Ponte, Jakob Skou Pedersen, PCAWG Drivers and Functional Interpretation Group, Rory Johnson, Carl Herrmann & PCAWG Consortium
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Summary:Joana Carlevaro-Fita, Andrés Lanzós et al. present the Cancer LncRNA Census (CLC), a manually curated dataset of 122 long noncoding RNAs (lncRNAs) with experimentally-validated functions in cancer based on data from the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. CLC lncRNAs have unique gene features, and a number display evidence for cancer-driving functions that are conserved from humans to mice.
Item Description:Gesehen am 16.04.2020
Physical Description:Online Resource
ISSN:2399-3642
DOI:10.1038/s42003-019-0741-7

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