Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
Joana Carlevaro-Fita, Andrés Lanzós et al. present the Cancer LncRNA Census (CLC), a manually curated dataset of 122 long noncoding RNAs (lncRNAs) with experimentally-validated functions in cancer based on data from the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. CLC lncRNAs...
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| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
05 February 2020
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| In: |
Communications biology
Year: 2020, Jahrgang: 3 |
| ISSN: | 2399-3642 |
| DOI: | 10.1038/s42003-019-0741-7 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s42003-019-0741-7 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s42003-019-0741-7 |
| Verfasserangaben: | Joana Carlevaro-Fita, Andrés Lanzós, Lars Feuerbach, Chen Hong, David Mas-Ponte, Jakob Skou Pedersen, PCAWG Drivers and Functional Interpretation Group, Rory Johnson, Carl Herrmann & PCAWG Consortium |
| Zusammenfassung: | Joana Carlevaro-Fita, Andrés Lanzós et al. present the Cancer LncRNA Census (CLC), a manually curated dataset of 122 long noncoding RNAs (lncRNAs) with experimentally-validated functions in cancer based on data from the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. CLC lncRNAs have unique gene features, and a number display evidence for cancer-driving functions that are conserved from humans to mice. |
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| Beschreibung: | Gesehen am 16.04.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 2399-3642 |
| DOI: | 10.1038/s42003-019-0741-7 |