Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture

RNA interactome capture allows the detailed investigation of RNA-bound proteomes. Here the authors describe enhanced RNA-interactome capture using LNA-modified probes for increased sensitivity and specificity.

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Bibliographic Details
Main Authors: Perez-Perri, Joel (Author) , Zhou, Yang (Author) , Hentze, Matthias W. (Author)
Format: Article (Journal)
Language:English
Published: 23 October 2018
In: Nature Communications
Year: 2018, Volume: 9
ISSN:2041-1723
DOI:10.1038/s41467-018-06557-8
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s41467-018-06557-8
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s41467-018-06557-8
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Author Notes:Joel I. Perez-Perri, Birgit Rogell, Thomas Schwarzl, Frank Stein, Yang Zhou, Mandy Rettel, Annika Brosig & Matthias W. Hentze
Description
Summary:RNA interactome capture allows the detailed investigation of RNA-bound proteomes. Here the authors describe enhanced RNA-interactome capture using LNA-modified probes for increased sensitivity and specificity.
Item Description:Gesehen am 21.04.2020
Physical Description:Online Resource
ISSN:2041-1723
DOI:10.1038/s41467-018-06557-8