Impact of community piped water coverage on re-infection with urogenital schistosomiasis in rural South Africa
Previously, we demonstrated that coverage of piped water in the seven years preceding a parasitological survey was strongly predictive of Schistosomiasis haematobium infection in a nested cohort of 1976 primary school children (Tanser, 2018). Here, we report on the prospective follow up of infected...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
[2020]
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| In: |
eLife
Year: 2020, Volume: 9 |
| ISSN: | 2050-084X |
| DOI: | 10.7554/eLife.54012 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.7554/eLife.54012
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| Author Notes: | Polycarp Mogeni, Alain Vandormael, Diego Cuadros, Christopher Appleton, Frank Tanser |
| Summary: | Previously, we demonstrated that coverage of piped water in the seven years preceding a parasitological survey was strongly predictive of Schistosomiasis haematobium infection in a nested cohort of 1976 primary school children (Tanser, 2018). Here, we report on the prospective follow up of infected members of this nested cohort (N = 333) for two successive rounds following treatment. Using a negative binomial regression fitted to egg count data, we found that every percentage point increase in piped water coverage was associated with 4.4% decline in intensity of re-infection (incidence rate ratio = 0.96, 95% CI: 0.93-0.98, p=0.004) among the treated children. We therefore provide further compelling evidence in support of the scaleup of piped water as an effective control strategy against Schistosoma haematobium transmission. |
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| Item Description: | Gesehen am 21.04.2020 |
| Physical Description: | Online Resource |
| ISSN: | 2050-084X |
| DOI: | 10.7554/eLife.54012 |