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Medulloblastomics revisited: biological and clinical insights from thousands of patients

This Review discusses recent genomic, epigenomic, transcriptomic and proteomic profiling studies of human medulloblastoma that have advanced our understanding of its disease subgroups. These efforts have provided new insights into the diverse biology of medulloblastomas that will hopefully lead to i...

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Bibliographic Details
Main Authors: Hovestadt, Volker (Author) , Ayrault, Olivier (Author) , Swartling, Fredrik J. (Author) , Robinson, Giles W. (Author) , Pfister, Stefan (Author) , Northcott, Paul A. (Author)
Format: Article (Journal)
Language:English
Published: 09 December 2019
In: Nature reviews. Cancer
Year: 2019, Volume: 20, Issue: 1, Pages: 42-56
ISSN:1474-1768
DOI:10.1038/s41568-019-0223-8
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s41568-019-0223-8
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s41568-019-0223-8
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Author Notes:Volker Hovestadt, Olivier Ayrault, Fredrik J. Swartling, Giles W. Robinson, Stefan M. Pfister, and Paul A. Northcott
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Summary:This Review discusses recent genomic, epigenomic, transcriptomic and proteomic profiling studies of human medulloblastoma that have advanced our understanding of its disease subgroups. These efforts have provided new insights into the diverse biology of medulloblastomas that will hopefully lead to improved diagnosis and therapy.
Item Description:Gesehen am 27.04.2020
Physical Description:Online Resource
ISSN:1474-1768
DOI:10.1038/s41568-019-0223-8

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