Medulloblastomics revisited: biological and clinical insights from thousands of patients
This Review discusses recent genomic, epigenomic, transcriptomic and proteomic profiling studies of human medulloblastoma that have advanced our understanding of its disease subgroups. These efforts have provided new insights into the diverse biology of medulloblastomas that will hopefully lead to i...
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| Hauptverfasser: | , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
09 December 2019
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| In: |
Nature reviews. Cancer
Year: 2019, Jahrgang: 20, Heft: 1, Pages: 42-56 |
| ISSN: | 1474-1768 |
| DOI: | 10.1038/s41568-019-0223-8 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s41568-019-0223-8 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s41568-019-0223-8 
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| Verfasserangaben: | Volker Hovestadt, Olivier Ayrault, Fredrik J. Swartling, Giles W. Robinson, Stefan M. Pfister, and Paul A. Northcott |
| Zusammenfassung: | This Review discusses recent genomic, epigenomic, transcriptomic and proteomic profiling studies of human medulloblastoma that have advanced our understanding of its disease subgroups. These efforts have provided new insights into the diverse biology of medulloblastomas that will hopefully lead to improved diagnosis and therapy. |
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| Beschreibung: | Gesehen am 27.04.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1474-1768 |
| DOI: | 10.1038/s41568-019-0223-8 |