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Salivary cortisol levels and anxiety in melanoma patients undergoing sentinel lymph node excision under local anesthesia versus general anesthesia: a prospective study

Sentinel lymph node excision (SLNE) can be performed in tumescent local anesthesia (TLA) or general anesthesia (GA). Perioperative cortisol level changes and anxiety are common in surgical interventions and might be influenced by the type of anesthesia. In this study, we intended to determine whethe...

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Main Authors: Jansen, Philipp (Author) , Stoffels, Ingo (Author) , Müseler, Anne-Christine (Author) , Petri, Maximilian (Author) , Brinker, Titus Josef (Author) , Schedlowski, Manfred (Author) , Schadendorf, Dirk (Author) , Engler, Harald Raimund (Author) , Klode, Joachim (Author)
Format: Article (Journal)
Language:English
Published: 10 March 2020
In: World journal of surgical oncology
Year: 2020, Volume: 18, Pages: 1-8
ISSN:1477-7819
DOI:10.1186/s12957-020-01823-w
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12957-020-01823-w
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Author Notes:Philipp Jansen, Ingo Stoffels, Anne-Christine Müseler, Maximilian Petri, Titus J. Brinker, Manfred Schedlowski, Dirk Schadendorf, Harald Engler and Joachim Klode
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Summary:Sentinel lymph node excision (SLNE) can be performed in tumescent local anesthesia (TLA) or general anesthesia (GA). Perioperative cortisol level changes and anxiety are common in surgical interventions and might be influenced by the type of anesthesia. In this study, we intended to determine whether the type of anesthesia impacts the patients’ perioperative levels of salivary cortisol (primary outcome) and the feeling of anxiety evaluated by psychological questionnaires (secondary outcome).
Item Description:Gesehen am 28.04.2020
Physical Description:Online Resource
ISSN:1477-7819
DOI:10.1186/s12957-020-01823-w

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