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Nephroprotective effects of enalapril after (177Lu)-DOTATATE therapy using serial renal scintigraphies in a murine model of radiation-induced nephropathy

Radiation-induced nephropathy is still dose limiting in radionuclide therapy of neuroendocrine tumors. We investigated the nephroprotective potential of the angiotensine converting enzyme inhibiting drug enalpril after [177Lu]-DOTATATE therapy in a murine model of radiation-induced nephropathy by re...

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Main Authors: Ilhan, Harun (Author) , Wang, Hao (Author) , Gildehaus, Franz J. (Author) , Wängler, Carmen (Author) , Herrler, Tanja (Author) , Todica, Andrei (Author) , Schlichtiger, Julia (Author) , Cumming, Paul (Author) , Bartenstein, Peter (Author) , Hacker, Marcus (Author) , Haug, Alexander R. (Author)
Format: Article (Journal)
Language:English
Published: 11 August 2016
In: EJNMMI Research
Year: 2016, Volume: 6
ISSN:2191-219X
DOI:10.1186/s13550-016-0219-2
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13550-016-0219-2
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Author Notes:Harun Ilhan, Hao Wang, Franz J. Gildehaus, Carmen Wängler, Tanja Herrler, Andrei Todica, Julia Schlichtiger, Paul Cumming, Peter Bartenstein, Marcus Hacker and Alexander R. Haug
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Summary:Radiation-induced nephropathy is still dose limiting in radionuclide therapy of neuroendocrine tumors. We investigated the nephroprotective potential of the angiotensine converting enzyme inhibiting drug enalpril after [177Lu]-DOTATATE therapy in a murine model of radiation-induced nephropathy by renal scintigraphy.
Item Description:Im Titel ist der Ausdruck "177Lu" eckig geklammert
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Physical Description:Online Resource
ISSN:2191-219X
DOI:10.1186/s13550-016-0219-2

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