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Golgi stress mediates redox imbalance and ferroptosis in human cells

Hamed Alborzinia et al. show that Golgi-dispersing compounds trigger iron-dependent oxidative degradation of lipids, inducing a non-apoptotic cell death called ferroptosis. This study provides insight into the role of Golgi apparatus for preventing ferroptotic cell death through its cellular redox c...

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Hauptverfasser: Alborzinia, Hamed (VerfasserIn) , Ignashkova, Tatiana I. (VerfasserIn) , Dejure, Francesca Romana (VerfasserIn) , Gendarme, Mathieu (VerfasserIn) , Theobald, Jannick (VerfasserIn) , Wölfl, Stefan (VerfasserIn) , Lindemann, Ralph K. (VerfasserIn) , Reiling, Jan H. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 28 November 2018
In: Communications biology
Year: 2018, Jahrgang: 1, Pages: 1-15
ISSN:2399-3642
DOI:10.1038/s42003-018-0212-6
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s42003-018-0212-6
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s42003-018-0212-6
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Verfasserangaben:Hamed Alborzinia, Tatiana I. Ignashkova, Francesca R. Dejure, Mathieu Gendarme, Jannick Theobald, Stefan Wölfl, Ralph K. Lindemann & Jan H. Reiling

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