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Roadmap on biosensing and photonics with advanced nano-optical methods

This roadmap, through the contributions of ten groups worldwide, contains different techniques, methods and materials devoted to sensing in nanomedicine. Optics is used in different ways in the detection schemes. Raman, fluorescence and infrared spectroscopies, plasmonics, second harmonic generation...

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Main Authors: Fabrizio, Enzo Di (Author) , Schlücker, Sebastian (Author) , Wenger, Jérôme (Author) , Regmi, Raju (Author) , Rigneault, Hervé (Author) , Calafiore, Giuseppe (Author) , West, Melanie (Author) , Cabrini, Stefano (Author) , Fleischer, Monika (Author) , Hulst, Niek F. van (Author) , Garcia-Parajo, Maria F. (Author) , Pucci, Annemarie (Author) , Cojoc, Dan (Author) , Hauser, Charlotte A. E. (Author) , Ni, Ming (Author)
Format: Article (Journal)
Language:English
Published: 10 May 2016
In: Journal of optics
Year: 2016, Volume: 18, Issue: 6
ISSN:2040-8986
DOI:10.1088/2040-8978/18/6/063003
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1088/2040-8978/18/6/063003
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Author Notes:Enzo Di Fabrizio, Sebastian Schlücker, Jérôme Wenger, Raju Regmi, Hervé Rigneault, Giuseppe Calafiore, Melanie West, Stefano Cabrini, Monika Fleischer, Niek F. van Hulst, Maria F. Garcia-Parajo, Annemarie Pucci, Dan Cojoc, Charlotte A.E. Hauser and Ming Ni
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Summary:This roadmap, through the contributions of ten groups worldwide, contains different techniques, methods and materials devoted to sensing in nanomedicine. Optics is used in different ways in the detection schemes. Raman, fluorescence and infrared spectroscopies, plasmonics, second harmonic generation and optical tweezers are all used in applications from single molecule detection (both in highly diluted and in highly concentrated solutions) to single cell manipulation. In general, each optical scheme, through device miniaturization and electromagnetic field localization, exploits an intrinsic optical enhancement mechanism in order to increase the sensitivity and selectivity of the device with respect to the complex molecular construct. The materials used for detection include nanoparticles and nanostructures fabricated with different 2D and 3D lithographic methods. It is shown that sensitivity to a single molecule is already accessible whether the system under study is a single cell or a multitude of cells in a molecular mixture. Throughout the roadmap there is an attempt to foresee and to suggest future directions in this interdisciplinary field.
Item Description:Gesehen am 07.05.2020
Physical Description:Online Resource
ISSN:2040-8986
DOI:10.1088/2040-8978/18/6/063003

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