Ca2+/calmodulin-dependent protein kinase II-γ (CaMKIIγ) negatively regulates vascular smooth muscle cell proliferation and vascular remodeling

Vascular smooth muscle (VSM) expresses calcium/calmodulin-dependent protein kinase II (CaMKII)-δ and -γ isoforms. CaMKIIδ promotes VSM proliferation and vascular remodeling. We tested CaMKIIγ function in vascular remodeling after injury.

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Bibliographic Details
Main Authors: Saddouk, Fatima Z. (Author) , Sun, Li-Yan (Author) , Liu, Yong Feng (Author) , Jiang, Miao (Author) , Singer, Diane V. (Author) , Backs, Johannes (Author) , Riper, Dee Van (Author) , Ginnan, Roman (Author) , Schwarz, John J. (Author) , Singer, Harold A. (Author)
Format: Article (Journal)
Language:English
Published: 2016
In: The FASEB journal
Year: 2015, Volume: 30, Issue: 3, Pages: 1051-1064
ISSN:1530-6860
DOI:10.1096/fj.15-279158
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1096/fj.15-279158
Verlag, lizenzpflichtig, Volltext: https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.15-279158
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Author Notes:Fatima Z. Saddouk, Li-Yan Sun, Yong Feng Liu, Miao Jiang, Diane V. Singer, Johannes Backs, Dee Van Riper, Roman Ginnan, John J. Schwarz, and Harold A. Singer
Description
Summary:Vascular smooth muscle (VSM) expresses calcium/calmodulin-dependent protein kinase II (CaMKII)-δ and -γ isoforms. CaMKIIδ promotes VSM proliferation and vascular remodeling. We tested CaMKIIγ function in vascular remodeling after injury.
Item Description:First published: 13 November 2015
Gesehen am 07.05.2020
Physical Description:Online Resource
ISSN:1530-6860
DOI:10.1096/fj.15-279158