Prospective assessment of a gene signature potentially predictive of clinical benefit in metastatic melanoma patients following MAGE-A3 immunotherapeutic (PREDICT)

Genomic profiling of tumor tissue may identify gene signatures (GS) predictive of tumor response to treatment. We prospectively evaluated a GS linked to clinical benefit following MAGE-A3 immunotherapeutic in patients with advanced melanoma. One-year overall survival was similar in patients with and...

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Main Authors:	Saiag, Philippe (Author) , Gutzmer, R. (Author) , Ascierto, P. A. (Author) , Maio, M. (Author) , Grob, J. -J. (Author) , Murawa, P. (Author) , Dreno, B. (Author) , Ross, M. (Author) , Weber, J. (Author) , Hauschild, A. (Author) , Rutkowski, P. (Author) , Testori, A. (Author) , Levchenko, E. (Author) , Enk, Alexander (Author) , Misery, L. (Author) , Vanden Abeele, C. (Author) , Vojtek, I. (Author) , Peeters, O. (Author) , Brichard, V. G. (Author) , Therasse, P. (Author)
Format:	Article (Journal)
Language:	English
Published:	8 August 2016
In:	Annals of oncology Year: 2016, Volume: 27, Issue: 10, Pages: 1947-1953
ISSN:	1569-8041
DOI:	10.1093/annonc/mdw291
Online Access:	Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/annonc/mdw291 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0923753419359198
Author Notes:	P. Saiag, R. Gutzmer, P.A. Ascierto, M. Maio, J.-J. Grob, P. Murawa, B. Dreno, M. Ross, J. Weber, A. Hauschild, P. Rutkowski, A. Testori, E. Levchenko, A. Enk, L. Misery, C. Vanden Abeele, I. Vojtek, O. Peeters, V.G. Brichard & P. Therasse