Prospective assessment of a gene signature potentially predictive of clinical benefit in metastatic melanoma patients following MAGE-A3 immunotherapeutic (PREDICT)
Genomic profiling of tumor tissue may identify gene signatures (GS) predictive of tumor response to treatment. We prospectively evaluated a GS linked to clinical benefit following MAGE-A3 immunotherapeutic in patients with advanced melanoma. One-year overall survival was similar in patients with and...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
8 August 2016
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| In: |
Annals of oncology
Year: 2016, Jahrgang: 27, Heft: 10, Pages: 1947-1953 |
| ISSN: | 1569-8041 |
| DOI: | 10.1093/annonc/mdw291 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/annonc/mdw291 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0923753419359198 
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| Verfasserangaben: | P. Saiag, R. Gutzmer, P.A. Ascierto, M. Maio, J.-J. Grob, P. Murawa, B. Dreno, M. Ross, J. Weber, A. Hauschild, P. Rutkowski, A. Testori, E. Levchenko, A. Enk, L. Misery, C. Vanden Abeele, I. Vojtek, O. Peeters, V.G. Brichard & P. Therasse |
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| 520 | |a Genomic profiling of tumor tissue may identify gene signatures (GS) predictive of tumor response to treatment. We prospectively evaluated a GS linked to clinical benefit following MAGE-A3 immunotherapeutic in patients with advanced melanoma. One-year overall survival was similar in patients with and without the GS: the GS was not predictive of outcome after MAGE-A3 immunotherapeutic treatment. | ||
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