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Limited functional effects of subacute syngeneic bone marrow stromal cell transplantation after rat spinal cord contusion injury

Cell transplantation might be one means to improve motor, sensory, or autonomic recovery after traumatic spinal cord injury (SCI). Among the different cell types evaluated to date, bone marrow stromal cells (BMSCs) have received considerable interest due to their potential neuroprotective properties...

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Main Authors: Sandner, Beatrice (Author) , Ciatipis, Mareva (Author) , Motsch, Melanie (Author) , Soljanik, Irina (Author) , Weidner, Norbert (Author) , Blesch, Armin (Author)
Format: Article (Journal)
Language:English
Published: 2016
In: Cell transplantation
Year: 2015, Volume: 25, Issue: 1, Pages: 125-139
ISSN:1555-3892
DOI:10.3727/096368915X687679
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.3727/096368915X687679
Verlag, lizenzpflichtig, Volltext: https://journals.sagepub.com/doi/full/10.3727/096368915X687679
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Author Notes:Beatrice Sandner, Mareva Ciatipis, Melanie Motsch, Irina Soljanik, Norbert Weidner, and Armin Blesch
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Summary:Cell transplantation might be one means to improve motor, sensory, or autonomic recovery after traumatic spinal cord injury (SCI). Among the different cell types evaluated to date, bone marrow stromal cells (BMSCs) have received considerable interest due to their potential neuroprotective properties. However, uncertainty exists whether the efficacy of BMSCs after intraspinal transplantation justifies an invasive procedure. In the present study, we analyzed the effect of syngeneic BMSC transplantation following a moderate to severe rat spinal cord injury.
Item Description:Online prepub date: March 25, 2015
Gesehen am 08.05.2020
Physical Description:Online Resource
ISSN:1555-3892
DOI:10.3727/096368915X687679

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