An organelle-specific protein landscape identifies novel diseases and molecular mechanisms

Mutations in proteins that localize to primary cilia cause devastating diseases, yet the primary cilium is a poorly understood organelle. Here the authors use interaction proteomics to identify a network of human ciliary proteins that provides new insights into several biological processes and disea...

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Bibliographic Details

Main Authors:	Boldt, Karsten (Author) , Lu, Qianhao (Author) , Betts, Matthew J. (Author) , Russell, Robert B. (Author)
Format:	Article (Journal)
Language:	English
Published:	13 May 2016
In:	Nature Communications Year: 2016, Volume: 7
ISSN:	2041-1723
DOI:	10.1038/ncomms11491
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/ncomms11491 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/ncomms11491
Author Notes:	Karsten Boldt, Jeroen van Reeuwijk, Qianhao Lu, Konstantinos Koutroumpas, Thanh-Minh T. Nguyen, Yves Texier, Sylvia E. C. van Beersum, Nicola Horn, Jason R. Willer, Dorus A. Mans, Gerard Dougherty, Ideke J. C. Lamers, Karlien L. M. Coene, Heleen H. Arts, Matthew J. Betts, Tina Beyer, Emine Bolat, Christian Johannes Gloeckner, Khatera Haidari, Lisette Hetterschijt, Daniela Iaconis, Dagan Jenkins, Franziska Klose, Barbara Knapp, Brooke Latour, Stef J. F. Letteboer, Carlo L. Marcelis, Dragana Mitic, Manuela Morleo, Machteld M. Oud, Moniek Riemersma, Susan Rix, Paulien A. Terhal, Grischa Toedt, Teunis J. P. van Dam, Erik de Vrieze, Yasmin Wissinger, Ka Man Wu, Gordana Apic, Philip L. Beales, Oliver E. Blacque, Toby J. Gibson, Martijn A. Huynen, Nicholas Katsanis, Hannie Kremer, Heymut Omran, Erwin van Wijk, Uwe Wolfrum, François Kepes, Erica E. Davis, Brunella Franco, Rachel H. Giles, Marius Ueffing, Robert B. Russell, & Ronald Roepman