Relevance of Sp binding site polymorphism in WWOX for treatment outcome in pancreatic cancer

A genome-wide association study (GWAS) suggested inherited genetic single-nucleotide polymorphisms (SNPs) affecting overall survival (OS) in advanced pancreatic cancer. To identify robust clinical biomarkers, we tested the strongest reported candidate loci in an independent patient cohort, assessed...

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Main Authors:	Schirmer, Markus (Author) , Lüske, Claudia M. (Author) , Roppel, Sebastian (Author) , Schaudinn, Alexander (Author) , Zimmer, Christian (Author) , Pflüger, Ruben (Author) , Haubrock, Martin (Author) , Rapp, Jacobe (Author) , Güngör, Cenap (Author) , Bockhorn, Maximilian (Author) , Hackert, Thilo (Author) , Hank, Thomas (Author) , Strobel, Oliver (Author) , Werner, Jens (Author) , Izbicki, Jakob R. (Author) , Johnsen, Steven A. (Author) , Gaedcke, Jochen (Author) , Brockmöller, Jürgen (Author) , Ghadimi, B. Michael (Author)
Format:	Article (Journal)
Language:	English
Published:	February 8, 2016
In:	Journal of the National Cancer Institute Year: 2016, Volume: 108, Issue: 5
ISSN:	1460-2105
DOI:	10.1093/jnci/djv387
Online Access:	Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/jnci/djv387 Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/jnci/article/108/5/djv387/2412583
Author Notes:	Markus A. Schirmer, Claudia M. Lüske, Sebastian Roppel, Alexander Schaudinn, Christian Zimmer, Ruben Pflüger, Martin Haubrock, Jacobe Rapp, Cenap Güngör, Maximilian Bockhorn, Thilo Hackert, Thomas Hank, Oliver Strobel, Jens Werner, Jakob R. Izbicki, Steven A. Johnsen, Jochen Gaedcke, Jürgen Brockmöller, B. Michael Ghadimi