Determinants of cerebral hemodynamics during the Trail Making Test in schizophrenia

Patients with schizophrenia show deficits in cognitive functioning, and studies on cerebral hemodynamics have revealed aberrant patterns of mean cerebral blood flow velocity (MFV), an equivalent of cerebral blood flow (CBF). Therefore, we carried out a controlled study that assessed MFV in schizophr...

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Main Authors: Schüpbach, Daniel (Author) , Egger, Stephan T. (Author) , Boeker, Heinz (Author) , Duschek, Stefan (Author) , Vetter, Stefan (Author) , Seifritz, Erich (Author) , Herpertz, Sabine (Author)
Format: Article (Journal)
Language:English
Published: 17 September 2016
In: Brain and cognition
Year: 2016, Volume: 109, Pages: 96-104
ISSN:1090-2147
DOI:10.1016/j.bandc.2016.09.002
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.bandc.2016.09.002
Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0278262616302299
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Author Notes:Daniel Schuepbach, Stephan T. Egger, Heinz Boeker, Stefan Duschek, Stefan Vetter, Erich Seifritz, Sabine C. Herpertz
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Summary:Patients with schizophrenia show deficits in cognitive functioning, and studies on cerebral hemodynamics have revealed aberrant patterns of mean cerebral blood flow velocity (MFV), an equivalent of cerebral blood flow (CBF). Therefore, we carried out a controlled study that assessed MFV in schizophrenia during a well-known neuropsychological task, the Trail Making Test (TMT). We measured MFV in the middle cerebral arteries using functional transcranial Doppler sonography in 15 schizophrenia patients and 15 healthy subjects.
Item Description:Gesehen am 26.05.2020
Physical Description:Online Resource
ISSN:1090-2147
DOI:10.1016/j.bandc.2016.09.002