Cover Image

Next-generation sequencing-based detection of germline L1-mediated transductions

While active LINE-1 (L1) elements possess the ability to mobilize flanking sequences to different genomic loci through a process termed transduction influencing genomic content and structure, an approach for detecting polymorphic germline non-reference transductions in massively-parallel sequencing...

Full description

Saved in:
Bibliographic Details
Main Authors: Tica, Jelena (Author) , Lee, Eunjung (Author) , Untergasser, Andreas (Author) , Meiers, Sascha (Author) , Garfield, David A. (Author) , Gokcumen, Omer (Author) , Furlong, Eileen E.M. (Author) , Park, Peter J. (Author) , Stütz, Adrian M. (Author) , Korbel, Jan Oliver (Author)
Format: Article (Journal)
Language:English
Published: [2016]
In: BMC genomics
Year: 2016, Volume: 17, Issue: 1
ISSN:1471-2164
DOI:10.1186/s12864-016-2670-x
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12864-016-2670-x
Get full text
Author Notes:Jelena Tica, Eunjung Lee, Andreas Untergasser, Sascha Meiers, David A. Garfield, Omer Gokcumen, Eileen E.M. Furlong, Peter J. Park, Adrian M. Stütz, Jan O. Korbel
Description
Summary:While active LINE-1 (L1) elements possess the ability to mobilize flanking sequences to different genomic loci through a process termed transduction influencing genomic content and structure, an approach for detecting polymorphic germline non-reference transductions in massively-parallel sequencing data has been lacking.
Item Description:Gesehen am 27.05.2020
Physical Description:Online Resource
ISSN:1471-2164
DOI:10.1186/s12864-016-2670-x

Similar Items