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Intravenous artesunate reduces parasite clearance time, duration of intensive care, and hospital treatment in patients with severe malaria in europe: the TropNet severe malaria study

Intravenous artesunate improves survival in severe malaria, but clinical trial data from nonendemic countries are scarce. The TropNet severe malaria database was analyzed to compare outcomes of artesunate vs quinine treatment. Artesunate reduced parasite clearance time and duration of intensive care...

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Main Authors: Kurth, Florian Michael (Author) , Develoux, Michel (Author) , Mechain, Matthieu (Author) , Clerinx, Jan (Author) , Antinori, Spinello (Author) , Gjørup, Ida E. (Author) , Gascon, Joaquím (Author) , Mørch, Kristine (Author) , Nicastri, Emanuele (Author) , Ramharter, Michael (Author) , Bartoloni, Alessandro (Author) , Visser, Leo (Author) , Rolling, Thierry (Author) , Zanger, Philipp (Author) , Calleri, Guido (Author) , Salas-Coronas, Joaquín (Author) , Nielsen, Henrik (Author) , Just-Nübling, Gudrun (Author) , Neumayr, Andreas (Author) , Hachfeld, Anna (Author) , Schmid, Matthias L. (Author) , Antonini, Pietro (Author) , Pongratz, Peter (Author) , Kern, Peter (Author) , Saraiva da Cunha, José (Author) , Soriano-Arandes, Antoni (Author) , Schunk, Mirjam (Author) , Suttorp, Norbert (Author) , Hatz, Christoph (Author) , Zoller, Thomas (Author)
Format: Article (Journal)
Language:English
Published: 17 July 2015
In: Clinical infectious diseases
Year: 2015, Volume: 61, Issue: 9, Pages: 1441-1444
ISSN:1537-6591
DOI:10.1093/cid/civ575
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/cid/civ575
Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/cid/article/61/9/1441/432102
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Author Notes:Florian Kurth, Michel Develoux, Matthieu Mechain, Jan Clerinx, Spinello Antinori, Ida E. Gjørup, Joaquím Gascon, Kristine Mørch, Emanuele Nicastri, Michael Ramharter, Alessandro Bartoloni, Leo Visser, Thierry Rolling, Philipp Zanger, Guido Calleri, Joaquín Salas-Coronas, Henrik Nielsen, Gudrun Just-Nübling, Andreas Neumayr, Anna Hachfeld, Matthias L. Schmid, Pietro Antonini, Peter Pongratz, Peter Kern, José Saraiva da Cunha, Antoni Soriano-Arandes, Mirjam Schunk, Norbert Suttorp, Christoph Hatz, and Thomas Zoller
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Summary:Intravenous artesunate improves survival in severe malaria, but clinical trial data from nonendemic countries are scarce. The TropNet severe malaria database was analyzed to compare outcomes of artesunate vs quinine treatment. Artesunate reduced parasite clearance time and duration of intensive care unit and hospital treatment in European patients with imported severe malaria.
Item Description:Gesehen am 03.06.2020
Physical Description:Online Resource
ISSN:1537-6591
DOI:10.1093/cid/civ575

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