Automatic 3D segmentation and quantification of lenticulostriate arteries from high-resolution 7 Tesla MRA images

We propose a novel hybrid approach for automatic 3D segmentation and quantification of high-resolution 7 Tesla magnetic resonance angiography (MRA) images of the human cerebral vasculature. Our approach consists of two main steps. First, a 3D model-based approach is used to segment and quantify thic...

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Bibliographic Details
Main Authors: Liao, Wei (Author) , Rohr, Karl (Author) , Kang, Chang-Ki (Author) , Cho, Zang-Hee (Author) , Wörz, Stefan (Author)
Format: Article (Journal)
Language:English
Published: February 2016
In: IEEE transactions on image processing
Year: 2016, Volume: 25, Issue: 1, Pages: 400-413
ISSN:1941-0042
DOI:10.1109/TIP.2015.2499085
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1109/TIP.2015.2499085
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Author Notes:Wei Liao, Karl Rohr, Chang-Ki Kang, Zang-Hee Cho, and Stefan Wörz
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Summary:We propose a novel hybrid approach for automatic 3D segmentation and quantification of high-resolution 7 Tesla magnetic resonance angiography (MRA) images of the human cerebral vasculature. Our approach consists of two main steps. First, a 3D model-based approach is used to segment and quantify thick vessels and most parts of thin vessels. Second, remaining vessel gaps of the first step in low-contrast and noisy regions are completed using a 3D minimal path approach, which exploits directional information. We present two novel minimal path approaches. The first is an explicit approach based on energy minimization using probabilistic sampling, and the second is an implicit approach based on fast marching with anisotropic directional prior. We conducted an extensive evaluation with over 2300 3D synthetic images and 40 real 3D 7 Tesla MRA images. Quantitative and qualitative evaluation shows that our approach achieves superior results compared with a previous minimal path approach. Furthermore, our approach was successfully used in two clinical studies on stroke and vascular dementia.
Item Description:Gesehen am 04.06.2020
Physical Description:Online Resource
ISSN:1941-0042
DOI:10.1109/TIP.2015.2499085