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Exploiting noncovalent interactions in an imine-based covalent organic framework for Quercetin delivery

Covalent organic frameworks (COFs) are a new class of nanoporous polymeric vector showing promise as drug-delivery vehicles with high loading capacity and biocompatibility. The interaction between the carrier and the cargo is specifically tailored on a molecular level by H-bonding. Cell-proliferatio...

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Bibliographische Detailangaben
Hauptverfasser: Vyas, Vijay S. (VerfasserIn) , Vishwakarma, Medhavi (VerfasserIn) , Moudrakovski, Igor (VerfasserIn) , Haase, Frederik (VerfasserIn) , Savasci, Gökcen (VerfasserIn) , Ochsenfeld, Christian (VerfasserIn) , Spatz, Joachim P. (VerfasserIn) , Lotsch, Bettina V. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: [2016]
In: Advanced materials
Year: 2016, Jahrgang: 28, Heft: 39, Pages: 8749-8754
ISSN:1521-4095
DOI:10.1002/adma.201603006
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/adma.201603006
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201603006
Volltext
Verfasserangaben:Vijay S. Vyas, Medhavi Vishwakarma, Igor Moudrakovski, Frederik Haase, Gökcen Savasci, Christian Ochsenfeld, Joachim P. Spatz, and Bettina V. Lotsch
Beschreibung
Zusammenfassung:Covalent organic frameworks (COFs) are a new class of nanoporous polymeric vector showing promise as drug-delivery vehicles with high loading capacity and biocompatibility. The interaction between the carrier and the cargo is specifically tailored on a molecular level by H-bonding. Cell-proliferation studies indicate higher efficacy of the drug in cancer cells by nanocarrier delivery mediated by the COF.
Beschreibung:Gesehen am 04.06.2020
Beschreibung:Online Resource
ISSN:1521-4095
DOI:10.1002/adma.201603006

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