Patch testing to a textile dye mix by the International Contact Dermatitis Research Group
Disperse dyes are well-known contact sensitizers not included in the majority of commercially available baseline series. - Objective - To investigate the outcome of patch testing to a textile dye mix (TDM) consisting of 8 disperse dyes. - Methods - Two thousand four hundred ninety-th...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
Jul 1, 2015
|
| In: |
Dermatitis
Year: 2015, Volume: 26, Issue: 4, Pages: 170-176 |
| ISSN: | 2162-5220 |
| DOI: | 10.1097/DER.0000000000000125 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/DER.0000000000000125 Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/dermatitis/Abstract/2015/07000/Patch_Testing_To_a_Textile_Dye_Mix_by_the.5.aspx 
|
| Author Notes: | Isaksson, Marléne MD, PhD; Ale, Iris MD; Andersen, Klaus E. MD, DMSc; Diepgen, Thomas MD, PhD; Goh, Chee-Leok MD, MRCP(UK), FRCPE, MMed; Goossens R, An Pharm, PhD; Jerajani, Hemangi MD, DV&D; Maibach, Howard I. MD; Sasseville, Denis MD, FRCPC; Bruze, Magnus MD, PhD |
| Summary: | Disperse dyes are well-known contact sensitizers not included in the majority of commercially available baseline series. - Objective - To investigate the outcome of patch testing to a textile dye mix (TDM) consisting of 8 disperse dyes. - Methods - Two thousand four hundred ninety-three consecutive dermatitis patients in 9 dermatology clinics were patch tested with a TDM 6.6%, consisting of Disperse (D) Blue 35, D Yellow 3, D Orange 1 and 3, D Red 1 and 17, all 1.0% each, and D Blue 106 and D Blue 124, each 0.3%. 90 reacted positively to the TDM. About 92.2% of the patients allergic to the TDM were also tested with the 8 separate dyes. - Results - Contact allergy to TDM was found in 3.6% (1.3-18.2) Simultaneous reactivity to p-phenylenediamine was found in 61.1% of the TDM-positive patients. Contact allergy to TDM and not to other p-amino-substituted sensitizers was diagnosed in 1.2%. The most frequent dye allergen in the TDM-positive patients was D Orange 3. - Conclusions - Over 30% of the TDM allergic patients had been missed if only the international baseline series was tested. Contact allergy to TDM could explain or contribute to dermatitis in over 20% of the patients. Textile dye mix should be considered for inclusion into the international baseline series. |
|---|---|
| Item Description: | Gesehen am 23.06.2020 |
| Physical Description: | Online Resource |
| ISSN: | 2162-5220 |
| DOI: | 10.1097/DER.0000000000000125 |