Transferrin receptor 2 is a potential novel therapeutic target for β-thalassemia: evidence from a murine model

Key Points. Deletion of BM Tfr2 ameliorates anemia and iron overload in a murine model of transfusion-independent thalassemia.Deletion of Tfr2 enhances transcr

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Main Authors: Artuso, Irene (Author) , Lidonnici, Maria Rosa (Author) , Altamura, Sandro (Author) , Mandelli, Giacomo (Author) , Pettinato, Mariateresa (Author) , Muckenthaler, Martina (Author) , Silvestri, Laura (Author) , Ferrari, Giuliana (Author) , Camaschella, Clara (Author) , Nai, Antonella (Author)
Format: Article (Journal)
Language:English
Published: September 12, 2018
In: Blood
Year: 2018, Volume: 132, Issue: 21, Pages: 2286-2297
ISSN:1528-0020
DOI:10.1182/blood-2018-05-852277
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1182/blood-2018-05-852277
Verlag, lizenzpflichtig, Volltext: https://ashpublications.org/blood/article/132/21/2286/39548/Transferrin-receptor-2-is-a-potential-novel
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Author Notes:Irene Artuso, Maria Rosa Lidonnici, Sandro Altamura, Giacomo Mandelli, Mariateresa Pettinato, Martina U. Muckenthaler, Laura Silvestri, Giuliana Ferrari, Clara Camaschella, and Antonella Nai
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Summary:Key Points. Deletion of BM Tfr2 ameliorates anemia and iron overload in a murine model of transfusion-independent thalassemia.Deletion of Tfr2 enhances transcr
Item Description:Gesehen am 08.06.2020
Physical Description:Online Resource
ISSN:1528-0020
DOI:10.1182/blood-2018-05-852277