MiRNA-221 is elevated in cystic fibrosis airway epithelial cells and regulates expression of ATF6

MicroRNA (miRNA) and messenger RNA (mRNA) expression differs in cystic fibrosis (CF) versus non-CF bronchial epithelium. Here, the role of miRNA in basal regulation of the transcription factor ATF6 was investigated in bronchial epithelial cells in vitro and in vivo.

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Bibliographic Details
Main Authors: Oglesby, Irene K. (Author) , Agrawal, Raman (Author) , Mall, Marcus A. (Author) , McElvaney, Noel G. (Author) , Greene, Catherine M. (Author)
Format: Article (Journal)
Language:English
Published: 07 January 2015
In: Molecular and Cellular Pediatrics
Year: 2015, Volume: 2, Issue: 1
ISSN:2194-7791
DOI:10.1186/s40348-014-0012-0
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s40348-014-0012-0
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Author Notes:Irene K. Oglesby, Raman Agrawal, Marcus A. Mall, Noel G. McElvane and Catherine M. Greene
Description
Summary:MicroRNA (miRNA) and messenger RNA (mRNA) expression differs in cystic fibrosis (CF) versus non-CF bronchial epithelium. Here, the role of miRNA in basal regulation of the transcription factor ATF6 was investigated in bronchial epithelial cells in vitro and in vivo.
Item Description:Gesehen am 22.06.2020
Physical Description:Online Resource
ISSN:2194-7791
DOI:10.1186/s40348-014-0012-0