Treatment perspectives for medication-related osteonecrosis of the jaw (MRONJ)

The medication-related osteonecrosis of the jaw (MRONJ) is believed to be a therapy-resistant entity. Although the application of the recommended conservative and surgical treatment regimens have returned variable success rates, the increased awareness and experience with MRONJ suggests that surgica...

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Bibliographic Details
Main Authors: Ristow, Oliver (Author) , Otto, Sven (Author) , Troeltzsch, Matthias (Author) , Hohlweg-Majert, Bettina (Author) , Pautke, Christoph (Author)
Format: Article (Journal)
Language:English
Published: [2015]
In: Journal of cranio-maxillofacial surgery
Year: 2014, Volume: 43, Issue: 2, Pages: 290-293
ISSN:1878-4119
DOI:10.1016/j.jcms.2014.11.014
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.jcms.2014.11.014
Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S1010518214003205
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Author Notes:Oliver Ristow, Sven Otto, Matthias Troeltzsch, Bettina Hohlweg-Majert, Christoph Pautke
Description
Summary:The medication-related osteonecrosis of the jaw (MRONJ) is believed to be a therapy-resistant entity. Although the application of the recommended conservative and surgical treatment regimens have returned variable success rates, the increased awareness and experience with MRONJ suggests that surgical therapy can halt the progression of the disease, thereby allowing a histology-based diagnosis of the osteonecrosis. Surgical treatment protocols can achieve success rates of over 90% and novel techniques such as the visualization of bone fluorescence can assist in the intra-operative delineation of the osteonecrosis and standardize the procedure.
Item Description:Available online 22 November 2014
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Physical Description:Online Resource
ISSN:1878-4119
DOI:10.1016/j.jcms.2014.11.014