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Effects of early and late diabetic neuropathy on sciatic nerve block duration and neurotoxicity in Zucker diabetic fatty rats

The neuropathy of type II diabetes mellitus (DM) is increasing in prevalence worldwide. We aimed to test the hypothesis that in a rodent model of type II DM, neuropathy would lead to increased neurotoxicity and block duration after lidocaine-induced sciatic nerve block when compared with control ani...

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Main Authors: Lirk, Philipp (Author) , Verhamme, C. (Author) , Boeckh, R. (Author) , Stevens, M. F. (Author) , ten Hoope, W. (Author) , Gerner, P. (Author) , Blumenthal, S. (Author) , de Girolami, U. (Author) , van Schaik, I. N. (Author) , Hollmann, Markus W. (Author) , Picardi, Susanne (Author)
Format: Article (Journal)
Language:English
Published: 2015
In: British journal of anaesthesia
Year: 2014, Volume: 114, Issue: 2, Pages: 319-326
ISSN:1471-6771
DOI:10.1093/bja/aeu270
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/bja/aeu270
Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0007091217317245
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Author Notes:P. Lirk, C. Verhamme, R. Boeckh, M.F. Stevens, W. ten Hoope, P. Gerner, S. Blumenthal, U. de Girolami, I.N. van Schaik, M.W. Hollmann and S. Picardi
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Summary:The neuropathy of type II diabetes mellitus (DM) is increasing in prevalence worldwide. We aimed to test the hypothesis that in a rodent model of type II DM, neuropathy would lead to increased neurotoxicity and block duration after lidocaine-induced sciatic nerve block when compared with control animals.
Item Description:Advance access publication 21 August 2014
Gesehen am 26.06.2020
Physical Description:Online Resource
ISSN:1471-6771
DOI:10.1093/bja/aeu270

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