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Whither systems medicine?

New technologies to generate, store and retrieve medical and research data are inducing a rapid change in clinical and translational research and health care. Systems medicine is the interdisciplinary approach wherein physicians and clinical investigators team up with experts from biology, biostatis...

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Main Authors: Apweiler, Rolf (Author) , Beißbarth, Tim (Author) , Berthold, Michael (Author) , Blüthgen, Nils (Author) , Burmeister, Yvonne (Author) , Dammann, Olaf (Author) , Deutsch, Andreas (Author) , Feuerhake, Friedrich (Author) , Franke, Andre (Author) , Hasenauer, Jan (Author) , Hoffmann, Steve (Author) , Höfer, Thomas (Author) , Jansen, Peter LM (Author) , Kaderali, Lars (Author) , Klingmüller, Ursula (Author) , Koch, Ina (Author) , Kohlbacher, Oliver (Author) , Kuepfer, Lars (Author) , Lammert, Frank (Author) , Maier, Dieter (Author) , Pfeifer, Nico (Author) , Radde, Nicole (Author) , Rehm, Markus (Author) , Roeder, Ingo (Author) , Saez-Rodriguez, Julio (Author) , Sax, Ulrich (Author) , Schmeck, Bernd (Author) , Schuppert, Andreas (Author) , Seilheimer, Bernd (Author) , Theis, Fabian J. (Author) , Vera, Julio (Author) , Wolkenhauer, Olaf (Author)
Format: Article (Journal)
Language:English
Published: 2 March 2018
In: Experimental & molecular medicine
Year: 2018, Volume: 50, Issue: 3
ISSN:2092-6413
DOI:10.1038/emm.2017.290
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1038/emm.2017.290
Verlag, kostenfrei, Volltext: https://www.nature.com/articles/emm2017290
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Author Notes:Rolf Apweiler, Tim Beissbarth, Michael R Berthold, Nils Blüthgen, Yvonne Burmeister, Olaf Dammann, Andreas Deutsch, Friedrich Feuerhake, Andre Franke, Jan Hasenauer, Steve Hoffmann, Thomas Höfer, Peter LM Jansen, Lars Kaderali, Ursula Klingmüller, Ina Koch, Oliver Kohlbacher, Lars Kuepfer, Frank Lammert, Dieter Maier, Nico Pfeifer, Nicole Radde, Markus Rehm, Ingo Roeder, Julio Saez-Rodriguez, Ulrich Sax, Bernd Schmeck, Andreas Schuppert, Bernd Seilheimer, Fabian J. Theis, Julio Vera and Olaf Wolkenhauer
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Summary:New technologies to generate, store and retrieve medical and research data are inducing a rapid change in clinical and translational research and health care. Systems medicine is the interdisciplinary approach wherein physicians and clinical investigators team up with experts from biology, biostatistics, informatics, mathematics and computational modeling to develop methods to use new and stored data to the benefit of the patient. We here provide a critical assessment of the opportunities and challenges arising out of systems approaches in medicine and from this provide a definition of what systems medicine entails. Based on our analysis of current developments in medicine and healthcare and associated research needs, we emphasize the role of systems medicine as a multilevel and multidisciplinary methodological framework for informed data acquisition and interdisciplinary data analysis to extract previously inaccessible knowledge for the benefit of patients.
Item Description:Gesehen am 02.07.2020
Physical Description:Online Resource
ISSN:2092-6413
DOI:10.1038/emm.2017.290

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