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Export of virulence proteins by malaria-infected erythrocytes involves remodeling of host actin cytoskeleton

Key Points - Maurer's clefts are P falciparum-derived membranous structures within the host erythrocyte that are essential for parasite survival. PfPTP1 functions in a large complex of proteins and is required for linking of Maurer's clefts to the host actin cytoskeleton.

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Bibliographic Details
Main Authors: Rug, Melanie (Author) , Cyrklaff, Marek (Author) , Lemgruber, Leandro (Author) , Sanchez, Cecilia P. (Author) , Lanzer, Michael (Author) , Frischknecht, Friedrich (Author)
Format: Article (Journal)
Language:English
Published: November 27, 2014
In: Blood
Year: 2014, Volume: 124, Issue: 23, Pages: 3459-3468
ISSN:1528-0020
DOI:10.1182/blood-2014-06-583054
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1182/blood-2014-06-583054
Verlag, lizenzpflichtig, Volltext: https://ashpublications.org/blood/article/124/23/3459/33484/Export-of-virulence-proteins-by-malariainfected
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Author Notes:Melanie Rug, Marek Cyrklaff, Antti Mikkonen, Leandro Lemgruber, Simone Kuelzer, Cecilia P. Sanchez, Jennifer Thompson, Eric Hanssen, Matthew O’Neill, Christine Langer, Michael Lanzer, Friedrich Frischknecht, Alexander G. Maier, Alan F. Cowman
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Summary:Key Points - Maurer's clefts are P falciparum-derived membranous structures within the host erythrocyte that are essential for parasite survival. PfPTP1 functions in a large complex of proteins and is required for linking of Maurer's clefts to the host actin cytoskeleton.
Item Description:Gesehen am 07.07.2020
Physical Description:Online Resource
ISSN:1528-0020
DOI:10.1182/blood-2014-06-583054

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