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Generation of suppressive blood cells for control of allograft rejection

Immunosuppressants, used to prevent organ rejection, cause serious side effects. We induced specific immunosuppression towards the foreign transplant by administration of mitomycin C (MMC)-treated blood cells (MICs) from the organ donor, thus circumventing additional immunosuppressive medication.

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Bibliographic Details
Main Authors: Kleist, Christian (Author) , Şandra-Petrescu, Flavius Ionuţ (Author) , Jiga, Lucian (Author) , Dittmar, Laura (Author) , Mohr, Elisabeth (Author) , Greil, Johann (Author) , Mier, Walter (Author) , Becker, Luis Eduardo (Author) , Lang, Peter (Author) , Opelz, Gerhard (Author) , Terness, Peter (Author)
Format: Article (Journal)
Language:English
Published: 2015
In: Clinical science
Year: 2014, Volume: 128, Issue: 9, Pages: 593-607
ISSN:1470-8736
DOI:10.1042/CS20140258
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1042/CS20140258
Verlag, lizenzpflichtig, Volltext: https://portlandpress.com/clinsci/article/128/9/593/71278/Generation-of-suppressive-blood-cells-for-control
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Author Notes:Christian Kleist, Flavius Sandra-Petrescu, Lucian Jiga, Laura Dittmar, Elisabeth Mohr, Johann Greil, Walter Mier, Luis E. Becker, Peter Lang, Gerhard Opelz and Peter Terness
Description
Summary:Immunosuppressants, used to prevent organ rejection, cause serious side effects. We induced specific immunosuppression towards the foreign transplant by administration of mitomycin C (MMC)-treated blood cells (MICs) from the organ donor, thus circumventing additional immunosuppressive medication.
Item Description:Published as immediate publication 11 December 2014
Gesehen am 07.07.2020
Physical Description:Online Resource
ISSN:1470-8736
DOI:10.1042/CS20140258

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