Custodiol-N, the novel cardioplegic solution reduces ischemia/reperfusion injury after cardiopulmonary bypass

On the basis of Custodiol preservation and cardioplegic solution a novel cardioplegic solution was developed to improve the postischemic cardiac and endothelial function. In this study, we investigated whether its reduced cytotoxicity and its ability to reduce reactive oxygen species generation duri...

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Hauptverfasser: Veres, Gábor (VerfasserIn) , Radovits, Tamás (VerfasserIn) , Merkely, Béla (VerfasserIn) , Karck, Matthias (VerfasserIn) , Szabó, Gábor (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 28 February 2015
In: Journal of cardiothoracic surgery
Year: 2015, Jahrgang: 10, Heft: 1
ISSN:1749-8090
DOI:10.1186/s13019-015-0226-9
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13019-015-0226-9
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Verfasserangaben:Gábor Veres, Tamás Radovits, Béla Merkely, Matthias Karck, and Gábor Szabó
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Zusammenfassung:On the basis of Custodiol preservation and cardioplegic solution a novel cardioplegic solution was developed to improve the postischemic cardiac and endothelial function. In this study, we investigated whether its reduced cytotoxicity and its ability to reduce reactive oxygen species generation during hypoxic condition have beneficial effects in a clinically relevant canine model of CPB.
Beschreibung:Gesehen am 09.07.2020
Beschreibung:Online Resource
ISSN:1749-8090
DOI:10.1186/s13019-015-0226-9