Custodiol-N, the novel cardioplegic solution reduces ischemia/reperfusion injury after cardiopulmonary bypass
On the basis of Custodiol preservation and cardioplegic solution a novel cardioplegic solution was developed to improve the postischemic cardiac and endothelial function. In this study, we investigated whether its reduced cytotoxicity and its ability to reduce reactive oxygen species generation duri...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
28 February 2015
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| In: |
Journal of cardiothoracic surgery
Year: 2015, Volume: 10, Issue: 1 |
| ISSN: | 1749-8090 |
| DOI: | 10.1186/s13019-015-0226-9 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13019-015-0226-9
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| Author Notes: | Gábor Veres, Tamás Radovits, Béla Merkely, Matthias Karck, and Gábor Szabó |
| Summary: | On the basis of Custodiol preservation and cardioplegic solution a novel cardioplegic solution was developed to improve the postischemic cardiac and endothelial function. In this study, we investigated whether its reduced cytotoxicity and its ability to reduce reactive oxygen species generation during hypoxic condition have beneficial effects in a clinically relevant canine model of CPB. |
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| Item Description: | Gesehen am 09.07.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1749-8090 |
| DOI: | 10.1186/s13019-015-0226-9 |