Saturation-Recovery Myocardial T 1 -Mapping during Systole: Accurate and Robust Quantification in the Presence of Arrhythmia
Myocardial T1-mapping, a cardiac magnetic resonance imaging technique, facilitates a quantitative measure of fibrosis which is linked to numerous cardiovascular symptoms. To overcome the problems of common techniques, including lack of accuracy and robustness against partial-voluming and heart-rate...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
27 March 2018
|
| In: |
Scientific reports
Year: 2018, Jahrgang: 8 |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-018-23506-z |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s41598-018-23506-z Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s41598-018-23506-z 
|
| Verfasserangaben: | Nadja M. Meßner, Johannes Budjan, Dirk Loßnitzer, Theano Papavassiliu, Lothar R. Schad, Sebastian Weingärtner and Frank G. Zöllner |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1724132792 | ||
| 003 | DE-627 | ||
| 005 | 20220818144726.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200709s2018 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1038/s41598-018-23506-z |2 doi | |
| 035 | |a (DE-627)1724132792 | ||
| 035 | |a (DE-599)KXP1724132792 | ||
| 035 | |a (OCoLC)1264004055 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Meßner, Nadja |d 1989- |e VerfasserIn |0 (DE-588)1068932279 |0 (DE-627)821066145 |0 (DE-576)428305245 |4 aut | |
| 245 | 1 | 0 | |a Saturation-Recovery Myocardial T 1 -Mapping during Systole |b Accurate and Robust Quantification in the Presence of Arrhythmia |c Nadja M. Meßner, Johannes Budjan, Dirk Loßnitzer, Theano Papavassiliu, Lothar R. Schad, Sebastian Weingärtner and Frank G. Zöllner |
| 264 | 1 | |c 27 March 2018 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 09.07.2020 | ||
| 520 | |a Myocardial T1-mapping, a cardiac magnetic resonance imaging technique, facilitates a quantitative measure of fibrosis which is linked to numerous cardiovascular symptoms. To overcome the problems of common techniques, including lack of accuracy and robustness against partial-voluming and heart-rate variability, we introduce a systolic saturation-recovery T1-mapping method. The Saturation-Pulse Prepared Heart-rate independent Inversion-Recovery (SAPPHIRE) T1-mapping method was modified to enable imaging during systole. Phantom measurements were used to evaluate the insensitivity of systolic T1-mapping towards heart-rate variability. In-vivo feasibility and accuracy were demonstrated in ten healthy volunteers with native and post-contrast T1-mappping during systole and diastole. To show benefits in the presence of RR-variability, six arrhythmic patients underwent native T1-mapping. Resulting systolic SAPPHIRE T1-values showed no dependence on arrhythmia in phantom (CoV < 1%). In-vivo, significantly lower T1 (1563 ± 56 ms, precision: 84.8 ms) and ECV-values (0.20 ± 0.03) than during diastole (T1 = 1580 ± 62 ms, p = 0.0124; precision: 60.2 ms, p = 0.03; ECV = 0.21 ± 0.03, p = 0.0098) were measured, with a strong correlation of systolic and diastolic T1 (r = 0.89). In patients, mis-triggering-induced motion caused significant imaging artifacts in diastolic T1-maps, whereas systolic T1-maps displayed resilience to arrythmia. In conclusion, the proposed method enables saturation-recovery T1-mapping during systole, providing increased robustness against partial-voluming compared to diastolic imaging, for the benefit of T1-measurements in arrhythmic patients. | ||
| 700 | 1 | |a Budjan, Johannes |d 1984- |e VerfasserIn |0 (DE-588)1020241047 |0 (DE-627)691154244 |0 (DE-576)359777821 |4 aut | |
| 700 | 1 | |a Loßnitzer, Dirk |d 1972- |e VerfasserIn |0 (DE-588)124754031 |0 (DE-627)365721506 |0 (DE-576)29448325X |4 aut | |
| 700 | 1 | |a Papavassiliu, Theano |d 1970- |e VerfasserIn |0 (DE-588)1028853440 |0 (DE-627)731667417 |0 (DE-576)376292849 |4 aut | |
| 700 | 1 | |a Schad, Lothar R. |d 1956- |e VerfasserIn |0 (DE-588)1028817630 |0 (DE-627)731640241 |0 (DE-576)376271221 |4 aut | |
| 700 | 1 | |a Zöllner, Frank G. |d 1976- |e VerfasserIn |0 (DE-588)129580015 |0 (DE-627)473357054 |0 (DE-576)297732587 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Scientific reports |d [London] : Springer Nature, 2011 |g 8(2018) Artikel-Nummer 5251, 9 Seiten |h Online-Ressource |w (DE-627)663366712 |w (DE-600)2615211-3 |w (DE-576)346641179 |x 2045-2322 |7 nnas |a Saturation-Recovery Myocardial T 1 -Mapping during Systole Accurate and Robust Quantification in the Presence of Arrhythmia |
| 773 | 1 | 8 | |g volume:8 |g year:2018 |g extent:9 |a Saturation-Recovery Myocardial T 1 -Mapping during Systole Accurate and Robust Quantification in the Presence of Arrhythmia |
| 856 | 4 | 0 | |u https://doi.org/10.1038/s41598-018-23506-z |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.nature.com/articles/s41598-018-23506-z |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20200709 | ||
| 993 | |a Article | ||
| 994 | |a 2018 | ||
| 998 | |g 129580015 |a Zöllner, Frank G. |m 129580015:Zöllner, Frank G. |p 7 |y j | ||
| 998 | |g 1028817630 |a Schad, Lothar R. |m 1028817630:Schad, Lothar R. |p 5 | ||
| 998 | |g 1028853440 |a Papavassiliu, Theano |m 1028853440:Papavassiliu, Theano |d 60000 |e 60000PP1028853440 |k 0/60000/ |p 4 | ||
| 998 | |g 124754031 |a Loßnitzer, Dirk |m 124754031:Loßnitzer, Dirk |d 60000 |d 61000 |e 60000PL124754031 |e 61000PL124754031 |k 0/60000/ |k 1/60000/61000/ |p 3 | ||
| 998 | |g 1020241047 |a Budjan, Johannes |m 1020241047:Budjan, Johannes |d 60000 |d 62900 |e 60000PB1020241047 |e 62900PB1020241047 |k 0/60000/ |k 1/60000/62900/ |p 2 | ||
| 999 | |a KXP-PPN1724132792 |e 3722752035 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"language":["eng"],"person":[{"given":"Nadja","role":"aut","family":"Meßner","display":"Meßner, Nadja"},{"role":"aut","given":"Johannes","display":"Budjan, Johannes","family":"Budjan"},{"family":"Loßnitzer","display":"Loßnitzer, Dirk","role":"aut","given":"Dirk"},{"given":"Theano","role":"aut","family":"Papavassiliu","display":"Papavassiliu, Theano"},{"display":"Schad, Lothar R.","family":"Schad","given":"Lothar R.","role":"aut"},{"display":"Zöllner, Frank G.","family":"Zöllner","given":"Frank G.","role":"aut"}],"id":{"doi":["10.1038/s41598-018-23506-z"],"eki":["1724132792"]},"name":{"displayForm":["Nadja M. Meßner, Johannes Budjan, Dirk Loßnitzer, Theano Papavassiliu, Lothar R. Schad, Sebastian Weingärtner and Frank G. Zöllner"]},"physDesc":[{"extent":"9 S."}],"relHost":[{"disp":"Saturation-Recovery Myocardial T 1 -Mapping during Systole Accurate and Robust Quantification in the Presence of ArrhythmiaScientific reports","type":{"media":"Online-Ressource","bibl":"periodical"},"title":[{"title":"Scientific reports","title_sort":"Scientific reports"}],"note":["Gesehen am 12.07.24"],"pubHistory":["1, article number 1 (2011)-"],"origin":[{"publisherPlace":"[London] ; London","publisher":"Springer Nature ; Nature Publishing Group","dateIssuedKey":"2011","dateIssuedDisp":"2011-"}],"id":{"issn":["2045-2322"],"zdb":["2615211-3"],"eki":["663366712"]},"physDesc":[{"extent":"Online-Ressource"}],"recId":"663366712","part":{"extent":"9","text":"8(2018) Artikel-Nummer 5251, 9 Seiten","volume":"8","year":"2018"},"language":["eng"]}],"recId":"1724132792","type":{"media":"Online-Ressource","bibl":"article-journal"},"origin":[{"dateIssuedDisp":"27 March 2018","dateIssuedKey":"2018"}],"note":["Gesehen am 09.07.2020"],"title":[{"title":"Saturation-Recovery Myocardial T 1 -Mapping during Systole","title_sort":"Saturation-Recovery Myocardial T 1 -Mapping during Systole","subtitle":"Accurate and Robust Quantification in the Presence of Arrhythmia"}]} | ||
| SRT | |a MESSNERNADSATURATION2720 | ||