Cover Image

Analyses of gonadoblastoma Y (GBY)-locus and of Y centromere in Turner Syndrome patients

Mosaicism with cytogenetically visible Y chromosome is found in 5-6% of Turner Syndrome (TS) patients. Additionally, occult Y-chromosome derived material is increasingly found in patients with monosomy X when using more sensitive molecular techniques. These TS patients are at risk of developing gona...

Full description

Saved in:
Bibliographic Details
Main Authors: Knauer-Fischer, Sabine (Author) , Beşikoğlu, Banu (Author) , Inta, Ioana (Author) , Kneppo, Carolin (Author) , Vogt, Peter H. (Author) , Bettendorf, Markus (Author)
Format: Article (Journal)
Language:English
Published: 2015
In: Experimental and clinical endocrinology & diabetes
Year: 2014, Volume: 123, Issue: 1, Pages: 61-65
ISSN:1439-3646
DOI:10.1055/s-0034-1387734
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1055/s-0034-1387734
Verlag, lizenzpflichtig, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1387734
Get full text
Author Notes:S. Knauer-Fischer, B. Besikoglu, I. Inta, C. Kneppo, P.H. Vogt, M. Bettendorf
Description
Summary:Mosaicism with cytogenetically visible Y chromosome is found in 5-6% of Turner Syndrome (TS) patients. Additionally, occult Y-chromosome derived material is increasingly found in patients with monosomy X when using more sensitive molecular techniques. These TS patients are at risk of developing gonadoblastomas when the Y genes presumed to be involved in gonadoblastoma development (Gonadoblastoma-Y-locus; GBY) are present. Aim: To find occult Y-chromosome material in TS patients and to correlate the patient’s phenotype to Y-chromosome material.
Item Description:Publikationsdatum: 14. Oktober 2014 (online)
Gesehen am 10.07.2020
Physical Description:Online Resource
ISSN:1439-3646
DOI:10.1055/s-0034-1387734

Similar Items