Buchumschlag

Analyses of gonadoblastoma Y (GBY)-locus and of Y centromere in Turner Syndrome patients

Mosaicism with cytogenetically visible Y chromosome is found in 5-6% of Turner Syndrome (TS) patients. Additionally, occult Y-chromosome derived material is increasingly found in patients with monosomy X when using more sensitive molecular techniques. These TS patients are at risk of developing gona...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Knauer-Fischer, Sabine (VerfasserIn) , Beşikoğlu, Banu (VerfasserIn) , Inta, Ioana (VerfasserIn) , Kneppo, Carolin (VerfasserIn) , Vogt, Peter H. (VerfasserIn) , Bettendorf, Markus (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2015
In: Experimental and clinical endocrinology & diabetes
Year: 2014, Jahrgang: 123, Heft: 1, Pages: 61-65
ISSN:1439-3646
DOI:10.1055/s-0034-1387734
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1055/s-0034-1387734
Verlag, lizenzpflichtig, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1387734
Volltext
Verfasserangaben:S. Knauer-Fischer, B. Besikoglu, I. Inta, C. Kneppo, P.H. Vogt, M. Bettendorf
Beschreibung
Zusammenfassung:Mosaicism with cytogenetically visible Y chromosome is found in 5-6% of Turner Syndrome (TS) patients. Additionally, occult Y-chromosome derived material is increasingly found in patients with monosomy X when using more sensitive molecular techniques. These TS patients are at risk of developing gonadoblastomas when the Y genes presumed to be involved in gonadoblastoma development (Gonadoblastoma-Y-locus; GBY) are present. Aim: To find occult Y-chromosome material in TS patients and to correlate the patient’s phenotype to Y-chromosome material.
Beschreibung:Publikationsdatum: 14. Oktober 2014 (online)
Gesehen am 10.07.2020
Beschreibung:Online Resource
ISSN:1439-3646
DOI:10.1055/s-0034-1387734

Ähnliche Einträge