β-catenin-independent roles of Wnt/LRP6 signaling
Wnt/LRP6 signaling is best known for the β-catenin-dependent regulation of target genes. However, pathway branches have recently emerged, including Wnt/STOP signaling, which act independently of β-catenin and transcription. We review here the molecular mechanisms underlying β-catenin-independent Wnt...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
24 August 2016
|
| In: |
Trends in cell biology
Year: 2016, Volume: 26, Issue: 12, Pages: 956-967 |
| ISSN: | 1879-3088 |
| DOI: | 10.1016/j.tcb.2016.07.009 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.tcb.2016.07.009 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0962892416301027 
|
| Author Notes: | Sergio P. Acebron and Christof Niehrs |
| Summary: | Wnt/LRP6 signaling is best known for the β-catenin-dependent regulation of target genes. However, pathway branches have recently emerged, including Wnt/STOP signaling, which act independently of β-catenin and transcription. We review here the molecular mechanisms underlying β-catenin-independent Wnt/LRP6 signaling cascades and their implications for cell biology, development, and physiology. |
|---|---|
| Item Description: | Gesehen am 20.07.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1879-3088 |
| DOI: | 10.1016/j.tcb.2016.07.009 |