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Identification of cis-regulatory modules encoding temporal dynamics during development

Developmental transcriptional regulatory networks are circuits of transcription factors (TFs) and cis-acting DNA elements (Cis Regulatory Modules, CRMs) that dynamically control expression of downstream genes. Comprehensive knowledge of these networks is an essential step towards our understanding o...

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Main Authors: Potier, Delphine (Author) , Seyres, Denis (Author) , Guichard, Céline (Author) , Iche-Torres, Magali (Author) , Aerts, Stein (Author) , Herrmann, Carl (Author) , Perrin, Laurent (Author)
Format: Article (Journal)
Language:English
Published: 27 June 2014
In: BMC genomics
Year: 2014, Volume: 15
ISSN:1471-2164
DOI:10.1186/1471-2164-15-534
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2164-15-534
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Author Notes:Delphine Potier, Denis Seyres, Céline Guichard, Magali Iche-Torres, Stein Aerts, Carl Herrmann and Laurent Perrin
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Summary:Developmental transcriptional regulatory networks are circuits of transcription factors (TFs) and cis-acting DNA elements (Cis Regulatory Modules, CRMs) that dynamically control expression of downstream genes. Comprehensive knowledge of these networks is an essential step towards our understanding of developmental processes. However, this knowledge is mostly based on genome-wide mapping of transcription factor binding sites, and therefore requires prior knowledge regarding the TFs involved in the network.
Item Description:Gesehen am 23.07.2020
Physical Description:Online Resource
ISSN:1471-2164
DOI:10.1186/1471-2164-15-534

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